Registered Nurse salary in St. Louis, MO
Median pay, St. Louis metro
$83,180/year
about $39.99 an hour full-time
Middle half earns $77,410 – $100,230
Half of registered nurses in the St. Louis metro area earn more than $83,180 a year and half earn less. That's 15% lower than the national median of $97,550, and ranks #29 of the 30 big metro areas we track for this job.
Pay range
| Percentile | Yearly | Hourly* |
|---|---|---|
| 10th (entry level) | $63,440 | $30.50 |
| 25th | $77,410 | $37.22 |
| Median (50th) | $83,180 | $39.99 |
| 75th | $100,230 | $48.19 |
| 90th (top earners) | $104,460 | $50.22 |
*Yearly pay divided by 2,080 hours (40 hours × 52 weeks), the full-time basis BLS uses.
Is your offer fair?
For a registered nurse job in the St. Louis metro area, here's how an offer compares:
- Below market under $77,410 ($37.22/hr). Fine for a first job in the field, otherwise worth negotiating.
- Typical $77,410 to $100,230 ($37.22 to $48.19/hr). The middle half of what people in this job earn.
- Strong offer over $100,230 ($48.19/hr). Higher than three quarters of workers here.
Before you accept
- Shift differentials for nights and weekends can add a lot on top of the base rate, so ask for them in writing.
- Sign-on bonuses often come with a clawback if you leave within one or two years. Check the terms before you count on it.
- Ask about nurse-to-patient ratios and mandatory overtime, since they shape the job far more than the posting suggests.
Also watch for the common warning signs in the posting itself: 15 job posting red flags.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, 2025, St. Louis metro. Occupation: Registered Nurses (SOC 29-1141). Figures cover wage and salary workers and don't include bonuses, benefits or overtime.