Medical Assistant salary in St. Louis, MO
Median pay, St. Louis metro
$44,710/year
about $21.50 an hour full-time
Middle half earns $38,550 – $47,600
Half of medical assistants in the St. Louis metro area earn more than $44,710 a year and half earn less. That's 2% lower than the national median of $45,690, and ranks #21 of the 30 big metro areas we track for this job.
Pay range
| Percentile | Yearly | Hourly* |
|---|---|---|
| 10th (entry level) | $36,670 | $17.63 |
| 25th | $38,550 | $18.53 |
| Median (50th) | $44,710 | $21.50 |
| 75th | $47,600 | $22.88 |
| 90th (top earners) | $48,620 | $23.38 |
*Yearly pay divided by 2,080 hours (40 hours × 52 weeks), the full-time basis BLS uses.
Is your offer fair?
For a medical assistant job in the St. Louis metro area, here's how an offer compares:
- Below market under $38,550 ($18.53/hr). Fine for a first job in the field, otherwise worth negotiating.
- Typical $38,550 to $47,600 ($18.53 to $22.88/hr). The middle half of what people in this job earn.
- Strong offer over $47,600 ($22.88/hr). Higher than three quarters of workers here.
Before you accept
- Certification (such as CMA or RMA) can raise pay and open more roles, and some employers pay for it.
- Check whether the role is front office, back office or both, since mixed roles are often paid like single ones.
- Ask about guaranteed hours: some clinics cut hours on slow days.
Also watch for the common warning signs in the posting itself: 15 job posting red flags.
Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, 2025, St. Louis metro. Occupation: Medical Assistants (SOC 31-9092). Figures cover wage and salary workers and don't include bonuses, benefits or overtime.